The origins of the Industrial Chemistry and Chemical Engineering Department of the Politecnico di Milano date back to 1883, when a laboratory for Technological Chemistry was established in the former "Regio Istituto Tecnico Superiore"(founded in 1863) and was housed in the Rectory Palace of Via Cavour in Milan. Luigi Gabba was the director of the laboratory until 1914. In 1923 the "Regio Istituto Tecnico Superiore" became the "Regia Scuola di Ingegneria di Milano" and in 1927 it moved to the present location in Piazza Leonardo da Vinci.
Politecnico di Milano Main Building
It was in 1928 that the Institute of Industrial Chemistry was established. The chairman position was first held by Mario Giacomo Levi who had been appointed full professor of Industrial Chemistry.
In 1937 the "Regia Scuola di Ingegneria" became the "Regio Politecnico di Milano", and the next year Mario Giacomo Levi was removed from his position due to the newly introduced Racial Laws. Giulio Natta then came from Turin to replace him as full professor of Industrial Chemistry and chairman of the Institute.

Giulio Natta ,1963 Nobel Prize for Chemistry
It was in 1945 that the "Regio Politecnico" finally took its present title of Politecnico.
M.G. Levi returned and continued his work until 1953. The same year, the Insitute set up a Laboratory for Testing of Plastic Materials.
In 1963 Giulio Natta and Karl Ziegler were awarded the Nobel
Prize for Chemistry for their discovery of stereospecific polymerization in 1954. Over about 20 years, Natta and his colleagues carried out intensive research in this area, producing over 800 scientific publications and nearly
300 industrial patents. Giulio Natta left his position in 1973 and died six
years later.
In 1981 the Institute of Industrial Chemistry was named in his honour and became Dipartimento di Chimica Industriale e Ingegneria Chimica "Giulio Natta" in 1982.